VIT-3

Contents: Each film coated tablet contains: Thiamine Mononitrate 100mg. Cyanocobalamin 50mcg.

Indications
:
Oral

Dosage:
For therapeutic use, 2-4 tablets of Vitamins (Vit-3) should be administered daily until acute symptoms subside. Chronic cases may require longer therapy.

Contraindications
: Contraindicated in patients with history of hypersensitivity to the components. Cyanocobalamin should not be given to patients with suspected Vitamin B12 deficiency without confirmation of the diagnosis.

Special Precautions: Cyanocobalamin (Vitamin B12) Should not be used to treat megaloblastic anemia of pregnancy. Administration of doses greater then 10mcg of vitamin B12 daily may produce a haematological response in patients with folate deficiency; indiscriminate use may mask the precise diagnosis. Cyanocobalamin or hydoxocobalamin should, if possible, not be given to patients with suspected vitamin B12 deficiency without first confirming the diagnosis. Regular monitoring of the blood is advisable.

Adverse Drug Reactions
: Adverse effects seldom occur after oral administration of thiamine and cyanocobalamin, but hypersensitivity reactions have been reported after parental administration. Hypersensitivity reactions to thiamine ranged from very mild to very rarely, anaphylactic shock. Hypersensitivity reactions have occured rarely following oral large doses of pyridoxine is associated with the development of severe peropheral neuropathies.

Drug Interactions
: Drugs that increase the requirement for pyridoxine include hydralazine, isoniazid, penicillamine and oral contraceptives, neomycin, aminosalicylic acid, histamine H2-antagonists and colchicine may reduce the absorption of vitamin B12 from the gastrointestinal tract. Oral contraceptives may reduce serum concentrations of Vitamin B12 should be taken into account when performing assays for blood concentration.

MIMS Class: Vitamin B-Complex/ with C

ATC Classification
: A11DB- Vitamin B1 in combination with vitamin B6 and/or vitamin B12; Used as dietary supplements.

Regulatory Classification: Rx
 
Reference:

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